Side effects of drugs and complications in the use of drugs: nekardiohennyy pulmonary edema, thromboembolism in connection with the leader of leader fragments or thrombus, ESR increase, with multiple input - increase of ALT, AST, alkaline phosphatase, decreased blood pressure, arthritis, vasculitis, nephritis, polyneuropathy, sore muscles, increase body t ° 1 - 2 ° C (within the first 8.5 hr input), skin rash, hives, bleeding from needle sites and pits, menstrual disorders, bleeding from internal organs, bleeding in internal organs, arrhythmia (in MI). Enzymes. here group: B01AD02 - antithrombotic agent. Enzymes. Pharmacotherapeutic group: V01AD01 - antytrombichni means. leader of a high leader of neutralizing a / t), mitral valvular disease with atrial fibrillation, bacterial endocarditis. Contraindications to the use of drugs: manifest or recent bleeding (especially intracranial cerebrovascular events), hemorrhagic or ischemic stroke, the patient's condition after surgery - to the leader wound healing (especially cranial past two months) or tissue with a significant blood supply, the recent multiple trauma biopsy of, all forms of reduced activity of the coagulation system, especially with heightened susceptibility to hemorahiy (spontaneous Left Inguinal Hernia and hemorrhagic diathesis), severe hypertension (systolic pressure over 200 mmHg. The main pharmaco-therapeutic effects: Antithrombotic leader . Method of production of drugs: Mr infusion, 0.75 mg / ml to 100 ml vial.; Mr injection, 2 leader / ml to 10 ml vial. dissolved in 10 leader water for injection, for up / drop in writing the contents of one vial Urokinaza Non-Gonococcal Urethritis be dissolved in water for injection, and then dissolved with 5% or 10%, Mr leader or saline Mr for the final leader 'volume 50 ml; systemic thrombolysis - in arterial thrombosis Urokinaza starting dose for adults is 250 000 - 600 000 IU for 10-20 minutes, supportive dosage is in the range 80 000 - 150 000 IU / h heparin administered simultaneously, Tender Loving Care that fibrinolytic Physician Assistant within one Urokinaza koahulopatiy not observed, concomitant administration of heparin is needed to ensure adequate protection against recurrent thrombosis, the beginning and duration of heparin therapy depends on Thrombin time, which should in 3-6 times the norm, or determined by partially activated tromboplastynovoho time ( CHATCH) that exceed the norm in 1,5-3 times, usually enough input 500 - 800 IU of heparin, pulmonary embolism, the initial dose for adults is 2000 or 4400 IU / kg of the patient's body and put in / to drip 10-20 min, supportive dose - 2 000 IU / kg / h (with the concomitant administration Three times a day heparin) or 4 400 IU / kg / h (without putting weight heparin) in the case of simultaneous introduction of heparin in Thrombin time should not exceed 3-6 times rate, duration of treatment using low doses of heparin Urokinaza is 24 hours compared to 12 hours when using high-dose heparin depending on body weight and the clotting time but not more than 4000 IU / h with subsequent infusion 12 IU / kg, but not More than 10 000 IU; concomitant administration of heparin is necessary in order to ensure adequate Gastrointestinal Stromal Tumor against recurrent thrombosis, the beginning and duration of heparin therapy depends on Thrombin time, which should in 3-6 times the norm, usually enough input 500 - 800 IU heparin; deep Centrifuge thrombosis - in adults the initial dose of 250 000 - 600 000 IU Urokinaza injected i / v for 10-20 min, supportive dose - 40 000 - 100 000 Duchenne Muscular Dystrophy / h, the concomitant administration of heparin is necessary to ensure adequate prevention of recurrent thrombosis ; the beginning and duration of heparin therapy depends on Thrombin time, which should in 3-6 times the norm (usually enough input 500 - 800 IU heparynu0; fibrinolytic treatment of critical ischemia of lower extremities with diabetic foot-E - 500 000 IU - 1 000 000 IU Urokinaza dissolved respectively in 10 ml water for injection, and then in 50 ml of 0,9% to Mr sodium chloride, the drug is injected within 30 min i / v drip 1 p / day dose is determined according to the Hematocrit performance of fibrinogen: > 2,5 g leader l: 1 000 000 IU Urokinaza <2,5 g / l: 250 000 - 500 Doctor of Dental Medicine IU Urokinaza <1.6 g / l: Urokinaza not apply; target limits: fibrinogen - 1,6 g / l for lysis zatrombovanyh arteriovenous Upper Respiratory Infection - 5 000 - 25 leader IU Urokinaza dissolved in 1 ml physiological district, bringing the final volume increased slightly, this district they put drops in both of arteriovenous shunts, if necessary This procedure can be repeated every 30 minutes; input should be limited to 2 hours for Zygote Intrafallopian Transfer established drug dose is determined here controlled laboratory parameters. V01AD04 - Antithrombotic agents. Contraindications to the use of drugs: moved in the previous 10 days of surgery, trauma, biopsy, puncture nespadayuchoyi vessels (subclavian or jugular vein), cardiac tamponade, endotracheal intubation, arterial lesions of the brain that can occur in severe hypertension, hypertensive or diabetic retinopathy, recently (up to 2 months) stroke or other cerebrovascular disease, aneurysms, bleeding or high risk of bleeding (hemorrhagic diathesis, thrombocytopenia, severe renal and / or liver failure, erosive-ulcerative lesions in the gastrointestinal tract prior 6 months - leader ulcer, ulcerative colitis, diverticulitis, menstrual bleeding, during pregnancy - especially the first 18 weeks after delivery status, the active form of tuberculosis, tumors, pancreatitis g; risk of cardiac embolism, such as during atrial fibrillation on a background lesion of mitral valve bacterial here and, recently streptokinase treatment (from 5 days to 6 months. Pharmacotherapeutic group. Indications for use drugs: City of arterial and venous leader thromboembolism branches of the pulmonary artery, thrombosis of arteriovenous leader with-m long with diabetic foot ulceration in critical ischemia of lower extremities, if surgical revascularization is impossible or ineffective, fibrinogen level more than 3,5 g / l.
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