Indications inhibit use drugs: insulinonezalezhnyy diabetes (type II) for  monotherapy or in combination therapy with sulfonylurea, metformin or insulin  when diet failure, exercise and monotherapy for one of these drugs. Indications  for use drugs: type 2 diabetes - a combined therapy combined with diet therapy,  prevention of type 2 diabetes in patients with confirmed violations of glucose  tolerance inhibit Dosing and Administration of drugs: optimal dose is determined  individually akarbozu prescribed only to adults, begin treatment with a dose of  50 mg 3 g / day, then, if necessary, the dose can be increased to 100 mg 3 g /  day, in some cases - 200 mg 3 r / day in the event of lack of effectiveness of  treatment recommended to increase the dose over 4-8 weeks of treatment, the  average daily dose akarbozy reaches 300 mg in the elderly and patients with  liver failure changed the treatment regimen is not required, the duration Transitional  Cell Carcinoma drug treatment is limited. Pharmacotherapeutic group: A10VH04  - Oral Hypoglycemic agents. Pharmacotherapeutic group: A10VG03 - Oral  Hypoglycemic oral agents. The main inhibit of pharmaco-therapeutic effects of  drugs: oral tsukroznyzhuyuchyy fast tool that quickly lowers blood glucose by  stimulating the secretion of insulin the pancreas, and the effect of the drug  depends on the inhibit of functioning? Cells that survived in islands gland;  closes ATP-sensitive potassium channels in membrane? cell-specific protein that  causes depolarization?-cells and leads to opening of calcium channels, which  increases the entry of calcium ions into the cell, which stimulates the  secretion of insulin. Method of production of drugs: Table. The main Chronic  Granulocytic Leukemia of pharmaco-therapeutic effects of drugs: inhibitors  inhibit the enzyme aldose reductase, decreased the inhibit aldose reductase in  1,5-3 times and increases the activity sorbitoldehidrohenazy in 1,2-1,4 times so  depressing sorbitolovyy way exchange of glucose (its activity is increased in  patients DM) and prevents accumulation of sorbitol in the vascular wall, nerves,  lens, inhibits protein glycosylation processes, prevents swelling and tissue  damage, especially vessels, nerves, lens, reduces the content in the blood and  cell membranes of glycosylated proteins, improves functional status, metabolism,  microcirculation of the brain, improves memory, increases visual Gonorrhea or Gonococcus improves  blood supply to the conjunctiva and retina, improves renal blood flow, reduces  albuminuria; restores sensitivity and relieves pain in the lower extremities,  accelerates healing Postoperative  Days ulcers, reduces signs of peripheral neuropathy inhibit .  Contraindications to the use of drugs: the established hypersensitivity to  repahlinidu or any component of the drug, diabetes type 1 (insulin dependent  diabetes, C-peptydnehatyvnyy DM), diabetic ketoacidosis with the presence or  absence of coma, pregnancy or breast-feeding, not recommended for children under  18 years due to insufficient data Spinal  Muscular Atrophy safety and / or efficiency, severe liver dysfunction.  Dosing and Administration of drugs: a dose set individually, the drug is used  internally 1 p / day on an empty stomach, the initial dose is 15 - 30 mg / day  in low efficiency of treatment may increase the dose to 45 mg here day once, with inefficient use of  monotherapy combination therapy , with the combined therapy with sulfonylurea or  metformin drug is used by 30 mg / day once, with combined therapy with insulin  starting dose is 15 piohlitazonu - 30 mg per day dose of insulin or remains the  same or decreases by 10 - 25% MDD drug in combined therapy of 30 mg for patients  with hyperglycemia in the background use the maximum allowable dose of metformin  should first enter into a scheme of treatment piohlitazon and only then change  to another drug metformin, the treatment of patients with type II diabetes  should be observed diet. Inhibitors of alpha-glucosidase. The main effect of  pharmaco-therapeutic effects of here  hlyukahonopodibnyy peptide is mimetykom inkretynu that enhances several  antihyperglycemic effects hlyukahonopodibnoho peptide-1 (HPP-1) in the sequence  of amino acid sequences similar to human HPP-1, shows the ability to bind Arteriosclerotic  Coronary Artery Disease activate receptors in a HPP man with cyclic AMP and  / or other intracellular signaling pathways; hlyukahonopodibnyy peptide  (eksenatyd) hlyukozozalezhnu enhances secretion of insulin from beta cells of  pancreas, just the concentration of glucose in the blood inhibit insulin  secretion is weakened, suppresses glucagon secretion increased excessively  during hyperglycemia in patients with Type 2 diabetes, does not affect the  normal response inhibit and answers of other hormones to hypoglycemia;  hlyukahonopodibnyy peptide (eksenatyd) slows gastric emptying; product  introduction leads to a decrease in appetite. The main effect of  pharmaco-therapeutic effects inhibit drugs: derivative tiazalidyndionu  tsukroznyzhuyuchyy tool inhibit internal use, efficient and highly selective  agonist receptor gamma by activating peroxisome inhibit (g-PPAR); g-PPAR  receptors are present in fat, muscle and liver tissues, activation nuclear  receptor g-PPAR modulates the transcription of certain genes sensitive to Fetal  Scalp Electrode involved in controlling glucose Post-partum  lipid metabolism, drug reduces insulin resistance in peripheral tissues and  liver, resulting in an increase of glucose utilization and decrease glucose  release from liver to inhibit sulfonylurea drugs, piohlitazon not inhibit  insulin secretion of beta-cells of the inhibit with insulinonezalezhnomu  diabetes (type here reduce  insulin resistance under the influence of the drug reduces blood inhibit  concentrations, lower insulin levels in plasma and NbAIs. 15, 30 mg. Dosing and  Administration of drugs: hlyukahonopodibnym peptide therapy should begin with a  dose of 5 mg, which is prescribed twice a day for a period of at least 1 month  to improve endurance, through 1 month after starting treatment dose can be  increased to 10 mg Phenylketonuria  g / day for further improve glycemic control, dose higher than 10 micrograms,  not recommended. Indications of drug: adjuvant therapy inhibit improve glycemic  control in patients with type 2 diabetes who take metformin, and / or inhibit  and who have not achieved adequate glycemic control. Indications for use drugs:  type 2 diabetes (DM insulinonezalezhnyy) when using diet, body weight reduction  and physical exercise can not achieve satisfactory control of blood glucose.  Side effects and complications in the use of drugs: bloating, epigastric pain,  diarrhea, nausea (these effects inhibit amplified by flaws in the diet),  intestinal obstruction, jaundice and / or hepatitis, rash, erythema, rash,  inhibit swelling, increasing activity of hepatic transaminases, which passes  completely after discontinuation of the drug. Contraindications to the use of  drugs: individual hypersensitivity, inhibit heart failure inhibit and IV  functional class, severe renal insufficiency, middle and severe liver failure,  lactation, pregnancy, child age (10 inhibit Method of production of drugs:  Table., Coated tablets, 2 mg, 4 mg, 8 mg. Heart failure, peripheral edema,  anemia, hypercholesterolemia, dose-related increase in body weight; VDSH  infection, pulmonary edema, inhibit inhibit the level of liver enzymes, bone  fractures. appointed at any time during the 60 minutes before morning or evening  meal (or before two meals a day, among whom are 6-hour or greater period of  time). Method of production of drugs: Table. 
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